One of the conditions for high quality work in any field of activity is the ability to perform it. This ability among other things requires a certain state of physical and mental health. The medical professions require a lot of dedication, both physical and psycho-emotional costs due to the complexity of tasks, diverse contacts, responsibility, risk for both patients and employees. All of the above can lead to the development of burnout syndrome. Each professional group in health care system has its own characteristics that can lead to the development of this syndrome, so it needs in separate study. In this paper, we studied the severity of the burnout syndrome among the medical staff of a psychiatric hospital. The severity of the syndrome was determined by the method of V.V.Boyko, which provides for the allocation of three phases: tension, resistance, exhaustion. The first is characterized by dissatisfaction with oneself, feelings, anxiety and depression; the second - by the economy of emotions, reduction of professional responsibilities; the third – by the emotional detachment, the presence of psychosomatic manifestations. The severity of the listed phases and individual symptoms was analyzed among 119 employees (doctors, nurses, junior medical staff). In general, the syndrome was formed in 39% of employees (in 42% it was in the stage of formation, in 19% it was absent). This distribution, as well as the distribution by individual manifestations of the syndrome, differed among people of different ages and different categories of personnel. Based on the study, recommendations for primary and secondary prevention of the syndrome were developed.